Farming, pesticide use and hairy-cell leukemia

Hairy cell leukemia-variant.

Hairy cell leukaemia variant is a very rare chronic lymphoproliferative disorder and is closely related to hairy cell leukemia. We hereby describe a case of hairy cell leukaemia variant for the first time in Saudi Arabia. An elderly Saudi man presented with pallor, massive splenomegaly, and moderate hepatomegaly. Hemoglobin was 7.7 g/dl, Platelets were 134 x109/l and white blood count was 140x1...

Hairy Cell Leukemia in a Young Male: An Unusual Presentation

Dear Editor-in-Chief A 28 yr male was presented in October 2015 at Medicine Outpatient Department, Safdarjung Hospital, New Delhi- India with generalized weakness, fever and cough for preceding 15 days. Clinicoradiologic examination revealed pallor, firm, non-tender splenomegaly measuring 13.7 cm and hepatomegaly (liver span - 16.9 cm). However, no lymphadenopathy was found.

Case 4: Hairy Cell Leukemia

Hairy Cell Leukemia (HCL) and Hairy Cell Leukemia Variant (HCL-V)

Cells from hairy cell leukemia (HCL) and hairy cell leukemia variant (HCL-V) have a distinct immunophenotype which is of a mature but not terminally differentiated activated B-cell. Although some similarities exist between these two conditions like the expression of B-cell activation marker CD103, CD11c and IgG heavy chain expression, differences exists between these two diseases. HCL is positi...

Treatment of hairy-cell leukemia.

AIRY CELL LEUKEMIA (HCL), or leukemic reticuH loendotheliosis, is a chronic lymphoproliferative disease that was first described as a distinct clinicopathologic entity by Bouroncle et a1 in 1958.' It is characterized by mononuclear cells of B-lymphocyte origin in the peripheral blood that have prominent cytoplasmic projections staining with tartrate-resistant acid phosphatase' and by its typica...